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Genome-wide analysis identifies colonic genes differentially associated with serum leptin and insulin concentrations in C57BL/6J mice fed a high-fat diet

Obesity-induced chronic inflammation is known to increase the risk of ulcerative colitis, Crohn’s disease, and colorectal cancer. Accumulating evidence suggests that leptin and insulin are key molecules linking obesity with diseases of the lower intestine. Here, we identified serum phenotype-associa...

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Detalles Bibliográficos
Autores principales:	Kim, Sung-Eun, Choo, Jinsil, Yoon, Joon, Chu, Jae Ryang, Bae, Yun Jung, Lee, Seungyeoun, Park, Taesung, Sung, Mi-Kyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295695/ https://www.ncbi.nlm.nih.gov/pubmed/28170448 http://dx.doi.org/10.1371/journal.pone.0171664

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