Subretinal Pigment Epithelial Deposition of Drusen Components Including Hydroxyapatite in a Primary Cell Culture Model

PURPOSE: Extracellular deposits containing hydroxyapatite, lipids, proteins, and trace metals that form between the basal lamina of the RPE and the inner collagenous layer of Bruch's membrane are hallmarks of early AMD. We examined whether cultured RPE cells could produce extracellular deposits...

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Detalles Bibliográficos
Autores principales: Pilgrim, Matthew G., Lengyel, Imre, Lanzirotti, Antonio, Newville, Matt, Fearn, Sarah, Emri, Eszter, Knowles, Jonathan C., Messinger, Jeffrey D., Read, Russell W., Guidry, Clyde, Curcio, Christine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295770/
https://www.ncbi.nlm.nih.gov/pubmed/28146236
http://dx.doi.org/10.1167/iovs.16-21060

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