The Role of Histone Protein Modifications and Mutations in Histone Modifiers in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia

While cancer has been long recognized as a disease of the genome, the importance of epigenetic mechanisms in neoplasia was acknowledged more recently. The most active epigenetic marks are DNA methylation and histone protein modifications and they are involved in basic biological phenomena in every c...

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Detalles Bibliográficos
Autores principales: Janczar, Szymon, Janczar, Karolina, Pastorczak, Agata, Harb, Hani, Paige, Adam J. W., Zalewska-Szewczyk, Beata, Danilewicz, Marian, Mlynarski, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295773/
https://www.ncbi.nlm.nih.gov/pubmed/28054944
http://dx.doi.org/10.3390/cancers9010002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295773/
https://www.ncbi.nlm.nih.gov/pubmed/28054944
http://dx.doi.org/10.3390/cancers9010002

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