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Epigenomic Regulation of Androgen Receptor Signaling: Potential Role in Prostate Cancer Therapy
Androgen receptor (AR) signaling remains the major oncogenic pathway in prostate cancer (PCa). Androgen-deprivation therapy (ADT) is the principle treatment for locally advanced and metastatic disease. However, a significant number of patients acquire treatment resistance leading to castration resis...
Autores principales: | Cucchiara, Vito, Yang, Joy C., Mirone, Vincenzo, Gao, Allen C., Rosenfeld, Michael G., Evans, Christopher P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295780/ https://www.ncbi.nlm.nih.gov/pubmed/28275218 http://dx.doi.org/10.3390/cancers9010009 |
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