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Epigenomic Regulation of Androgen Receptor Signaling: Potential Role in Prostate Cancer Therapy

Androgen receptor (AR) signaling remains the major oncogenic pathway in prostate cancer (PCa). Androgen-deprivation therapy (ADT) is the principle treatment for locally advanced and metastatic disease. However, a significant number of patients acquire treatment resistance leading to castration resis...

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Detalles Bibliográficos
Autores principales: Cucchiara, Vito, Yang, Joy C., Mirone, Vincenzo, Gao, Allen C., Rosenfeld, Michael G., Evans, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295780/
https://www.ncbi.nlm.nih.gov/pubmed/28275218
http://dx.doi.org/10.3390/cancers9010009

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