Tropomyosin Controls Sarcomere-like Contractions for Rigidity Sensing and Suppressing Growth on Soft Matrices

Cells test the rigidity of the extracellular matrix by applying forces to it through integrin adhesions. Recent measurements show that these forces are applied via local micrometre-scale contractions, but how contraction force is regulated by rigidity is unknown. Here we performed high temporal- and...

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Detalles Bibliográficos
Autores principales: Wolfenson, Haguy, Meacci, Giovanni, Liu, Shuaimin, Stachowiak, Matthew R., Iskratsch, Thomas, Ghassemi, Saba, Roca-Cusachs, Pere, O’Shaughnessy, Ben, Hone, James, Sheetz, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296190/
https://www.ncbi.nlm.nih.gov/pubmed/26619148
http://dx.doi.org/10.1038/ncb3277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296190/
https://www.ncbi.nlm.nih.gov/pubmed/26619148
http://dx.doi.org/10.1038/ncb3277

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