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Regulation of Epigenetic Modifiers, Including KDM6B, by Interferon-γ and Interleukin-4 in Human Macrophages

BACKGROUND: Interferon-γ (IFN-γ) or interleukin-4 (IL-4) drives widely different transcriptional programs in macrophages. However, how IFN-γ and IL-4 alter expression of histone-modifying enzymes involved in epigenetic regulation and how this affects the resulting phenotypic polarization is incomple...

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Detalles Bibliográficos
Autores principales:	Yıldırım-Buharalıoğlu, Gökçe, Bond, Mark, Sala-Newby, Graciela B., Hindmarch, Charles C. T., Newby, Andrew C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296311/ https://www.ncbi.nlm.nih.gov/pubmed/28228757 http://dx.doi.org/10.3389/fimmu.2017.00092

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