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Presynaptic Muscarinic Acetylcholine Receptors and TrkB Receptor Cooperate in the Elimination of Redundant Motor Nerve Terminals during Development
The development of the nervous system involves the overproduction of synapses but connectivity is refined by Hebbian activity-dependent axonal competition. The newborn skeletal muscle fibers are polyinnervated but, at the end of the competition process, some days later, become innervated by a single...
Autores principales: | Nadal, Laura, Garcia, Neus, Hurtado, Erica, Simó, Anna, Tomàs, Marta, Lanuza, Maria A., Cilleros, Victor, Tomàs, Josep |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296322/ https://www.ncbi.nlm.nih.gov/pubmed/28228723 http://dx.doi.org/10.3389/fnagi.2017.00024 |
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