Cargando…
Heated carrier fluids in decreasing propofol injection pain: a randomized, controlled trial
BACKGROUND: Propofol is a commonly used intravenous drug during anesthetic induction because of its rapid onset and short duration. However, the injection pain that patients experience is so severe that they recall the induction of anesthesia as the most painful part of the perioperative period. The...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Anesthesiologists
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296385/ https://www.ncbi.nlm.nih.gov/pubmed/28184264 http://dx.doi.org/10.4097/kjae.2017.70.1.33 |
_version_ | 1782505591974920192 |
---|---|
author | Youn, Ann Misun Hsu, Tzung-Min |
author_facet | Youn, Ann Misun Hsu, Tzung-Min |
author_sort | Youn, Ann Misun |
collection | PubMed |
description | BACKGROUND: Propofol is a commonly used intravenous drug during anesthetic induction because of its rapid onset and short duration. However, the injection pain that patients experience is so severe that they recall the induction of anesthesia as the most painful part of the perioperative period. Therefore, the objective of this study was to determine the effect of heated carrier fluids (40℃) in decreasing propofol injection pain. METHODS: A randomized, controlled clinical trial was conducted in 90 patients aged 18 to 65 who were scheduled for either elective or urgent surgery under general anesthesia classified as American Society of Anesthesiologists physical status I or II. Patients were allocated into the following 3 groups: 1) Group W (n = 30) who received 200 ml of heated carrier fluids for 20 minutes prior to propofol injection; 2) Group L (n = 30) who received 200 ml of heated carrier fluids for 20 minutes prior to 0.5 mg/kg 1%lidocaine 1 minute before propofol injection; 3) Group C (control group, n = 30) who received 200 ml of room temperature fluids prior to propofol injection. Pain was evaluated using verbal pain score (VPS). RESULTS: Group W and Group L showed significant reduction (P = 0.001) in the incidence and severity of injection pain compared to Group C. VPS scores were significantly lower in Group W and Group L compared to those of Group C. Incidence of propofol injection pain was statistically different between Group W (P = 0.005) and Group L (P = 0.037) compared to Group C, but not statistically different between Group W and Group L (P = 0.432). CONCLUSIONS: Both sole injection of heated carrier fluids and the combination of 0.5 mg/kg 1%lidocaine pretreatment effectively reduced propofol injection pain. |
format | Online Article Text |
id | pubmed-5296385 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | The Korean Society of Anesthesiologists |
record_format | MEDLINE/PubMed |
spelling | pubmed-52963852017-02-09 Heated carrier fluids in decreasing propofol injection pain: a randomized, controlled trial Youn, Ann Misun Hsu, Tzung-Min Korean J Anesthesiol Clinical Research Article BACKGROUND: Propofol is a commonly used intravenous drug during anesthetic induction because of its rapid onset and short duration. However, the injection pain that patients experience is so severe that they recall the induction of anesthesia as the most painful part of the perioperative period. Therefore, the objective of this study was to determine the effect of heated carrier fluids (40℃) in decreasing propofol injection pain. METHODS: A randomized, controlled clinical trial was conducted in 90 patients aged 18 to 65 who were scheduled for either elective or urgent surgery under general anesthesia classified as American Society of Anesthesiologists physical status I or II. Patients were allocated into the following 3 groups: 1) Group W (n = 30) who received 200 ml of heated carrier fluids for 20 minutes prior to propofol injection; 2) Group L (n = 30) who received 200 ml of heated carrier fluids for 20 minutes prior to 0.5 mg/kg 1%lidocaine 1 minute before propofol injection; 3) Group C (control group, n = 30) who received 200 ml of room temperature fluids prior to propofol injection. Pain was evaluated using verbal pain score (VPS). RESULTS: Group W and Group L showed significant reduction (P = 0.001) in the incidence and severity of injection pain compared to Group C. VPS scores were significantly lower in Group W and Group L compared to those of Group C. Incidence of propofol injection pain was statistically different between Group W (P = 0.005) and Group L (P = 0.037) compared to Group C, but not statistically different between Group W and Group L (P = 0.432). CONCLUSIONS: Both sole injection of heated carrier fluids and the combination of 0.5 mg/kg 1%lidocaine pretreatment effectively reduced propofol injection pain. The Korean Society of Anesthesiologists 2017-02 2016-12-01 /pmc/articles/PMC5296385/ /pubmed/28184264 http://dx.doi.org/10.4097/kjae.2017.70.1.33 Text en Copyright © the Korean Society of Anesthesiologists, 2017 http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Research Article Youn, Ann Misun Hsu, Tzung-Min Heated carrier fluids in decreasing propofol injection pain: a randomized, controlled trial |
title | Heated carrier fluids in decreasing propofol injection pain: a randomized, controlled trial |
title_full | Heated carrier fluids in decreasing propofol injection pain: a randomized, controlled trial |
title_fullStr | Heated carrier fluids in decreasing propofol injection pain: a randomized, controlled trial |
title_full_unstemmed | Heated carrier fluids in decreasing propofol injection pain: a randomized, controlled trial |
title_short | Heated carrier fluids in decreasing propofol injection pain: a randomized, controlled trial |
title_sort | heated carrier fluids in decreasing propofol injection pain: a randomized, controlled trial |
topic | Clinical Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296385/ https://www.ncbi.nlm.nih.gov/pubmed/28184264 http://dx.doi.org/10.4097/kjae.2017.70.1.33 |
work_keys_str_mv | AT younannmisun heatedcarrierfluidsindecreasingpropofolinjectionpainarandomizedcontrolledtrial AT hsutzungmin heatedcarrierfluidsindecreasingpropofolinjectionpainarandomizedcontrolledtrial |