A Numbers Game: Ribosome Densities, Bacterial Growth, and Antibiotic-Mediated Stasis and Death

We postulate that the inhibition of growth and low rates of mortality of bacteria exposed to ribosome-binding antibiotics deemed bacteriostatic can be attributed almost uniquely to these drugs reducing the number of ribosomes contributing to protein synthesis, i.e., the number of effective ribosomes...

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Detalles Bibliográficos
Autores principales: Levin, Bruce R., McCall, Ingrid C., Perrot, Véronique, Weiss, Howard, Ovesepian, Armen, Baquero, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296603/
https://www.ncbi.nlm.nih.gov/pubmed/28174311
http://dx.doi.org/10.1128/mBio.02253-16

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