A Novel Phosphoregulatory Switch Controls the Activity and Function of the Major Catalytic Subunit of Protein Kinase A in Aspergillus fumigatus

Invasive aspergillosis (IA), caused by the filamentous fungal pathogen Aspergillus fumigatus, is a major cause of death among immunocompromised patients. The cyclic AMP/protein kinase A (PKA) signaling pathway is essential for hyphal growth and virulence of A. fumigatus, but the mechanism of regulat...

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Detalles Bibliográficos
Autores principales: Shwab, E. Keats, Juvvadi, Praveen R., Waitt, Greg, Soderblom, Erik J., Moseley, M. Arthur, Nicely, Nathan I., Asfaw, Yohannes G., Steinbach, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296607/
https://www.ncbi.nlm.nih.gov/pubmed/28174315
http://dx.doi.org/10.1128/mBio.02319-16

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