CXCL12/CXCR4 axis induced miR-125b promotes invasion and confers 5-fluorouracil resistance through enhancing autophagy in colorectal cancer

The activation of CXCL12/CXCR4 axis is associated with potential progression of cancer, such as invasion, metastasis and chemoresistance. However, the underlying mechanisms of CXCL12/CXCR4 axis and cancer progression have been poorly explored. We hypothesized that miRNAs might be critical downstream...

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Detalles Bibliográficos
Autores principales: Yu, Xinfeng, Shi, Wenna, Zhang, Yuhang, Wang, Xiaohui, Sun, Shiyue, Song, Zhiyu, Liu, Man, Zeng, Qiao, Cui, Shuxiang, Qu, Xianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296742/
https://www.ncbi.nlm.nih.gov/pubmed/28176874
http://dx.doi.org/10.1038/srep42226

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