MFN2 suppresses cancer progression through inhibition of mTORC2/Akt signaling

The mitochondrial GTPase mitofusin-2 (MFN2) has previously been reported to play a role in regulating cell proliferation, apoptosis and differentiation in a number of cell types. Here, we report that breast cancer patients with low MFN2 expression are associated with poor prognosis as compared to pa...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Ke, Chen, Guo, Li, Xiaobo, Wu, Xiaoqin, Chang, Zhijie, Xu, Jianhua, Zhu, Yu, Yin, Peihao, Liang, Xin, Dong, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296837/
https://www.ncbi.nlm.nih.gov/pubmed/28176801
http://dx.doi.org/10.1038/srep41718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296837/
https://www.ncbi.nlm.nih.gov/pubmed/28176801
http://dx.doi.org/10.1038/srep41718

Ejemplares similares