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Transcriptional firing helps to drive NETosis

Neutrophils are short-lived innate immune cells. These cells respond quickly to stimuli, and die within minutes to hours; the relevance of DNA transcription in dying neutrophils remains an enigma for several decades. Here we show that the transcriptional activity reflects the degree of DNA decondens...

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Detalles Bibliográficos
Autores principales: Khan, Meraj A., Palaniyar, Nades
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296899/
https://www.ncbi.nlm.nih.gov/pubmed/28176807
http://dx.doi.org/10.1038/srep41749