ISL1 is a major susceptibility gene for classic bladder exstrophy and a regulator of urinary tract development

Previously genome-wide association methods in patients with classic bladder exstrophy (CBE) found association with ISL1, a master control gene expressed in pericloacal mesenchyme. This study sought to further explore the genetics in a larger set of patients following-up on the most promising genomic...

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Detalles Bibliográficos
Autores principales: Zhang, Rong, Knapp, Michael, Suzuki, Kentaro, Kajioka, Daiki, Schmidt, Johanna M., Winkler, Jonas, Yilmaz, Öznur, Pleschka, Michael, Cao, Jia, Kockum, Christina Clementson, Barker, Gillian, Holmdahl, Gundela, Beaman, Glenda, Keene, David, Woolf, Adrian S., Cervellione, Raimondo M., Cheng, Wei, Wilkins, Simon, Gearhart, John P., Sirchia, Fabio, Di Grazia, Massimo, Ebert, Anne-Karolin, Rösch, Wolfgang, Ellinger, Jörg, Jenetzky, Ekkehart, Zwink, Nadine, Feitz, Wout F., Marcelis, Carlo, Schumacher, Johannes, Martinón-Torres, Federico, Hibberd, Martin Lloyd, Khor, Chiea Chuen, Heilmann-Heimbach, Stefanie, Barth, Sandra, Boyadjiev, Simeon A., Brusco, Alfredo, Ludwig, Michael, Newman, William, Nordenskjöld, Agneta, Yamada, Gen, Odermatt, Benjamin, Reutter, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296905/
https://www.ncbi.nlm.nih.gov/pubmed/28176844
http://dx.doi.org/10.1038/srep42170

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