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Osteoarthritis-associated basic calcium phosphate crystals activate membrane proximal kinases in human innate immune cells

BACKGROUND: Osteoarthritis (OA) is a chronic debilitating joint disorder of particularly high prevalence in the elderly population. Intra-articular basic calcium phosphate (BCP) crystals are present in the majority of OA joints and are associated with severe degeneration. They are known to activate...

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Detalles Bibliográficos
Autores principales:	Corr, Emma M., Cunningham, Clare C., Helbert, Laura, McCarthy, Geraldine M., Dunne, Aisling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296949/ https://www.ncbi.nlm.nih.gov/pubmed/28173838 http://dx.doi.org/10.1186/s13075-017-1225-0

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