Immunoselected STRO-3(+) mesenchymal precursor cells reduce inflammation and improve clinical outcomes in a large animal model of monoarthritis

BACKGROUND: The purpose of this study was to investigate the therapeutic efficacy of intravenously administered immunoselected STRO-3 + mesenchymal precursor cells (MPCs) on clinical scores, joint pathology and cytokine production in an ovine model of monoarthritis. METHODS: Monoarthritis was establ...

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Detalles Bibliográficos
Autores principales: Abdalmula, Anwar, Dooley, Laura M., Kaufman, Claire, Washington, Elizabeth A., House, Jacqueline V., Blacklaws, Barbara A., Ghosh, Peter, Itescu, Silviu, Bailey, Simon R., Kimpton, Wayne G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297153/
https://www.ncbi.nlm.nih.gov/pubmed/28173831
http://dx.doi.org/10.1186/s13287-016-0460-7

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