Cargando…
Hypomethylation of intron1 of α-synuclein gene does not correlate with Parkinson’s disease
Deregulation of α-synuclein encoding gene (SNCA) is one of the important facets of Parkinson’s disease (PD) research. DNA methylation status of SNCA-intron1 has been shown to regulate the α-synuclein expression. The present study is aimed at investigating whether methylation of SNCA-intron1 is assoc...
Autores principales: | Guhathakurta, Subhrangshu, Evangelista, Baggio A., Ghosh, Susmita, Basu, Sambuddha, Kim, Yoon-Seong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297217/ https://www.ncbi.nlm.nih.gov/pubmed/28173842 http://dx.doi.org/10.1186/s13041-017-0285-z |
Ejemplares similares
-
Regulation of Αlpha-Synuclein Gene (SNCA) by Epigenetic Modifier TET1 in Parkinson Disease
por: Guhathakurta, Subhrangshu, et al.
Publicado: (2022) -
Targeted attenuation of elevated histone marks at SNCA alleviates α‐synuclein in Parkinson's disease
por: Guhathakurta, Subhrangshu, et al.
Publicado: (2021) -
A novel tool for monitoring endogenous alpha-synuclein transcription by NanoLuciferase tag insertion at the 3′end using CRISPR-Cas9 genome editing technique
por: Basu, Sambuddha, et al.
Publicado: (2017) -
Transcriptional mutagenesis of α-synuclein caused by DNA oxidation in Parkinson’s disease pathogenesis
por: Basu, Sambuddha, et al.
Publicado: (2023) -
A novel extended form of alpha-synuclein 3′UTR in the human brain
por: Je, Goun, et al.
Publicado: (2018)