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Hypomethylation of intron1 of α-synuclein gene does not correlate with Parkinson’s disease

Deregulation of α-synuclein encoding gene (SNCA) is one of the important facets of Parkinson’s disease (PD) research. DNA methylation status of SNCA-intron1 has been shown to regulate the α-synuclein expression. The present study is aimed at investigating whether methylation of SNCA-intron1 is assoc...

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Detalles Bibliográficos
Autores principales: Guhathakurta, Subhrangshu, Evangelista, Baggio A., Ghosh, Susmita, Basu, Sambuddha, Kim, Yoon-Seong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297217/
https://www.ncbi.nlm.nih.gov/pubmed/28173842
http://dx.doi.org/10.1186/s13041-017-0285-z

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