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Genotoxic Effects of Culture Media on Human Pluripotent Stem Cells

Culture conditions play an important role in regulating the genomic integrity of Human Pluripotent Stem Cells (HPSCs). We report that HPSCs cultured in Essential 8 (E8) and mTeSR, two widely used media for feeder-free culturing of HPSCs, had many fold higher levels of ROS and higher mitochondrial po...

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Detalles Bibliográficos
Autores principales:	Prakash Bangalore, Megha, Adhikarla, Syama, Mukherjee, Odity, Panicker, Mitradas M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297241/ https://www.ncbi.nlm.nih.gov/pubmed/28176872 http://dx.doi.org/10.1038/srep42222

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