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Parathyroid hormone in renal transplanted recipients; a single center study

This investigation, aimed to study of intact parathormone (iPTH) and calcium (Ca) in a group of kidney transplanted patients and also we aimed to test the relationship of iPTH with various demographic data of kidney transplanted recipients. We studied 72 kidney transplanted persons with mean ages of...

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Detalles Bibliográficos
Autores principales: Nasri, Hamid, Rafieian-Kopaei, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Diabetic Nephropathy Prevention 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297467/
https://www.ncbi.nlm.nih.gov/pubmed/28197433
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author Nasri, Hamid
Rafieian-Kopaei, Mahmoud
author_facet Nasri, Hamid
Rafieian-Kopaei, Mahmoud
author_sort Nasri, Hamid
collection PubMed
description This investigation, aimed to study of intact parathormone (iPTH) and calcium (Ca) in a group of kidney transplanted patients and also we aimed to test the relationship of iPTH with various demographic data of kidney transplanted recipients. We studied 72 kidney transplanted persons with mean ages of 44±12 years. In this study, mean iPTH was 18.4±8.2 Pg/mL (median=16.5). A negative correlation of iPTH with creatinine clearance (r=-0.44, p<0.001) was seen. There was no any association between the time of kidney transplantation and serum iPTH (p>0.05). In contrast to previous findings, in our patients, there was not secondary hyperparathyroidism. The results revealed suppressed PTH secretion. The reason may be due to excessive intake of calcium and Vitamin D analogues, which may suppress parathyroid hormone secretion.
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spelling pubmed-52974672017-02-14 Parathyroid hormone in renal transplanted recipients; a single center study Nasri, Hamid Rafieian-Kopaei, Mahmoud J Nephropharmacol Brief Communication This investigation, aimed to study of intact parathormone (iPTH) and calcium (Ca) in a group of kidney transplanted patients and also we aimed to test the relationship of iPTH with various demographic data of kidney transplanted recipients. We studied 72 kidney transplanted persons with mean ages of 44±12 years. In this study, mean iPTH was 18.4±8.2 Pg/mL (median=16.5). A negative correlation of iPTH with creatinine clearance (r=-0.44, p<0.001) was seen. There was no any association between the time of kidney transplantation and serum iPTH (p>0.05). In contrast to previous findings, in our patients, there was not secondary hyperparathyroidism. The results revealed suppressed PTH secretion. The reason may be due to excessive intake of calcium and Vitamin D analogues, which may suppress parathyroid hormone secretion. Society of Diabetic Nephropathy Prevention 2013-01-01 /pmc/articles/PMC5297467/ /pubmed/28197433 Text en © 2013 The Author(s) Published by Society of Diabetic Nephropathy Prevention. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communication
Nasri, Hamid
Rafieian-Kopaei, Mahmoud
Parathyroid hormone in renal transplanted recipients; a single center study
title Parathyroid hormone in renal transplanted recipients; a single center study
title_full Parathyroid hormone in renal transplanted recipients; a single center study
title_fullStr Parathyroid hormone in renal transplanted recipients; a single center study
title_full_unstemmed Parathyroid hormone in renal transplanted recipients; a single center study
title_short Parathyroid hormone in renal transplanted recipients; a single center study
title_sort parathyroid hormone in renal transplanted recipients; a single center study
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297467/
https://www.ncbi.nlm.nih.gov/pubmed/28197433
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