Dmp1 Promoter-Driven Diphtheria Toxin Receptor Transgene Expression Directs Unforeseen Effects in Multiple Tissues

Mice harbouring a dentin matrix protein 1 (Dmp1) promoter-driven human diphtheria toxin (DT) receptor (HDTR) transgene (Tg) have recently been used to attain targeted ablation of osteocytes by diphtheria toxin (DT) treatment in order to define osteocyte function. Use of these Tg mice has asserted me...

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Detalles Bibliográficos
Autores principales: Al-Jazzar, Ahmed, Javaheri, Behzad, Prideaux, Matt, Boyde, Alan, Scudamore, Cheryl L., Cherifi, Chahrazad, Hay, Eric, Hopkinson, Mark, Boyd, Michael, Cohen-Solal, Martine, Farquharson, Colin, Pitsillides, Andrew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297664/
https://www.ncbi.nlm.nih.gov/pubmed/28035954
http://dx.doi.org/10.3390/ijms18010029

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