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Clinical Significance and Prognostic Relevance of Microsatellite Instability in Sporadic Colorectal Cancer Patients

Microsatellite instability (MSI) is a marker of the replication error phenotype. It is caused by impaired DNA mismatch repair processes (MMR), resulting in ineffectiveness of the mechanisms responsible for the DNA replication precision and postreplicative DNA repair. MSI underlies the pathogenesis o...

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Detalles Bibliográficos
Autores principales:	Copija, Angelika, Waniczek, Dariusz, Witkoś, Andrzej, Walkiewicz, Katarzyna, Nowakowska-Zajdel, Ewa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297741/ https://www.ncbi.nlm.nih.gov/pubmed/28067827 http://dx.doi.org/10.3390/ijms18010107

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