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Autocrine and Paracrine Mechanisms Promoting Chemoresistance in Cholangiocarcinoma
Resistance to conventional chemotherapeutic agents, a typical feature of cholangiocarcinoma, prevents the efficacy of the therapeutic arsenal usually used to combat malignancy in humans. Mechanisms of chemoresistance by neoplastic cholangiocytes include evasion of drug-induced apoptosis mediated by...
Autores principales: | Cadamuro, Massimiliano, Brivio, Simone, Spirli, Carlo, Joplin, Ruth E., Strazzabosco, Mario, Fabris, Luca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297782/ https://www.ncbi.nlm.nih.gov/pubmed/28098760 http://dx.doi.org/10.3390/ijms18010149 |
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