Inhibition of Autophagic Degradation Process Contributes to Claudin-2 Expression Increase and Epithelial Tight Junction Dysfunction in TNF-α Treated Cell Monolayers

Tight junction dysfunction plays a vital role in some chronic inflammatory diseases. Pro-inflammatory cytokines, especially tumor necrosis factor alpha (TNF-α), act as important factors in intestinal epithelial tight junction dysfunction during inflammatory conditions. Autophagy has also been shown...

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Detalles Bibliográficos
Autores principales: Zhang, Cong, Yan, Junkai, Xiao, Yongtao, Shen, Yujie, Wang, Jiazheng, Ge, Wensong, Chen, Yingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297790/
https://www.ncbi.nlm.nih.gov/pubmed/28106723
http://dx.doi.org/10.3390/ijms18010157

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