Design, Synthesis and Antifungal Activity Evaluation of New Thiazolin-4-ones as Potential Lanosterol 14α-Demethylase Inhibitors

Twenty-three thiazolin-4-ones were synthesized starting from phenylthioamide or thiourea derivatives by condensation with α-monochloroacetic acid or ethyl α-bromoacetate, followed by substitution in position 5 with various arylidene moieties. All the synthesized compounds were physico-chemically cha...

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Detalles Bibliográficos
Autores principales: Stana, Anca, Vodnar, Dan C., Tamaian, Radu, Pîrnău, Adrian, Vlase, Laurian, Ionuț, Ioana, Oniga, Ovidiu, Tiperciuc, Brînduşa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297809/
https://www.ncbi.nlm.nih.gov/pubmed/28106743
http://dx.doi.org/10.3390/ijms18010177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297809/
https://www.ncbi.nlm.nih.gov/pubmed/28106743
http://dx.doi.org/10.3390/ijms18010177

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