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Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation
CSP-1103 (formerly CHF5074) has been shown to reverse memory impairment and reduce amyloid plaque as well as inflammatory microglia activation in preclinical models of Alzheimer’s disease. Moreover, it was found to improve cognition and reduce brain inflammation in patients with mild cognitive impai...
Autores principales: | Porrini, Vanessa, Sarnico, Ilenia, Benarese, Marina, Branca, Caterina, Mota, Mariana, Lanzillotta, Annamaria, Bellucci, Arianna, Parrella, Edoardo, Faggi, Lara, Spano, Pierfranco, Imbimbo, Bruno Pietro, Pizzi, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297816/ https://www.ncbi.nlm.nih.gov/pubmed/28106772 http://dx.doi.org/10.3390/ijms18010184 |
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