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Methylglyoxal-Glyoxalase 1 Balance: The Root of Vascular Damage

The highly reactive dicarbonyl methylglyoxal (MGO) is mainly formed as byproduct of glycolysis. Therefore, high blood glucose levels determine increased MGO accumulation. Nonetheless, MGO levels are also increased as consequence of the ineffective action of its main detoxification pathway, the glyox...

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Detalles Bibliográficos
Autores principales:	Nigro, Cecilia, Leone, Alessia, Raciti, Gregory Alexander, Longo, Michele, Mirra, Paola, Formisano, Pietro, Beguinot, Francesco, Miele, Claudia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297820/ https://www.ncbi.nlm.nih.gov/pubmed/28106778 http://dx.doi.org/10.3390/ijms18010188

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