Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging

Operating at multiple levels of control, mesenchymal stem cells from adipose tissue (ADSCs) communicate with organ systems to adjust immune response, provide signals for differentiation, migration, enzymatic reactions, and to equilibrate the regenerative demands of balanced tissue homeostasis. The i...

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Detalles Bibliográficos
Autores principales: Gaur, Meenakshi, Dobke, Marek, Lunyak, Victoria V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297838/
https://www.ncbi.nlm.nih.gov/pubmed/28117680
http://dx.doi.org/10.3390/ijms18010208
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author Gaur, Meenakshi
Dobke, Marek
Lunyak, Victoria V.
author_facet Gaur, Meenakshi
Dobke, Marek
Lunyak, Victoria V.
author_sort Gaur, Meenakshi
collection PubMed
description Operating at multiple levels of control, mesenchymal stem cells from adipose tissue (ADSCs) communicate with organ systems to adjust immune response, provide signals for differentiation, migration, enzymatic reactions, and to equilibrate the regenerative demands of balanced tissue homeostasis. The identification of the mechanisms by which ADSCs accomplish these functions for dermatological rejuvenation and wound healing has great potential to identify novel targets for the treatment of disorders and combat aging. Herein, we review new insights into the role of adipose-derived stem cells in the maintenance of dermal and epidermal homeostasis, and recent advances in clinical applications of ADSCs related to dermatology.
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spelling pubmed-52978382017-02-10 Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging Gaur, Meenakshi Dobke, Marek Lunyak, Victoria V. Int J Mol Sci Review Operating at multiple levels of control, mesenchymal stem cells from adipose tissue (ADSCs) communicate with organ systems to adjust immune response, provide signals for differentiation, migration, enzymatic reactions, and to equilibrate the regenerative demands of balanced tissue homeostasis. The identification of the mechanisms by which ADSCs accomplish these functions for dermatological rejuvenation and wound healing has great potential to identify novel targets for the treatment of disorders and combat aging. Herein, we review new insights into the role of adipose-derived stem cells in the maintenance of dermal and epidermal homeostasis, and recent advances in clinical applications of ADSCs related to dermatology. MDPI 2017-01-20 /pmc/articles/PMC5297838/ /pubmed/28117680 http://dx.doi.org/10.3390/ijms18010208 Text en © 2017 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Gaur, Meenakshi
Dobke, Marek
Lunyak, Victoria V.
Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging
title Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging
title_full Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging
title_fullStr Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging
title_full_unstemmed Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging
title_short Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging
title_sort mesenchymal stem cells from adipose tissue in clinical applications for dermatological indications and skin aging
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297838/
https://www.ncbi.nlm.nih.gov/pubmed/28117680
http://dx.doi.org/10.3390/ijms18010208
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