What Do We Know about Opioids and the Kidney?

Evidence suggests a link between opioid use and kidney disease. This review summarizes the known renal manifestations of opioid use including its role in acute and chronic kidney injury. Both the direct and indirect effects of the drug, and the context which leads to the development of renal failure...

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Detalles Bibliográficos
Autores principales: Mallappallil, Mary, Sabu, Jacob, Friedman, Eli A., Salifu, Moro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297852/
https://www.ncbi.nlm.nih.gov/pubmed/28117754
http://dx.doi.org/10.3390/ijms18010223
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author Mallappallil, Mary
Sabu, Jacob
Friedman, Eli A.
Salifu, Moro
author_facet Mallappallil, Mary
Sabu, Jacob
Friedman, Eli A.
Salifu, Moro
author_sort Mallappallil, Mary
collection PubMed
description Evidence suggests a link between opioid use and kidney disease. This review summarizes the known renal manifestations of opioid use including its role in acute and chronic kidney injury. Both the direct and indirect effects of the drug, and the context which leads to the development of renal failure, are explored. While commonly used safely for pain control and anesthesia in those with kidney disease, the concerns with respect to side effects and toxicity of opioids are addressed. This is especially relevant with the worldwide increase in the use of opioids for medical and recreational use.
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spelling pubmed-52978522017-02-10 What Do We Know about Opioids and the Kidney? Mallappallil, Mary Sabu, Jacob Friedman, Eli A. Salifu, Moro Int J Mol Sci Review Evidence suggests a link between opioid use and kidney disease. This review summarizes the known renal manifestations of opioid use including its role in acute and chronic kidney injury. Both the direct and indirect effects of the drug, and the context which leads to the development of renal failure, are explored. While commonly used safely for pain control and anesthesia in those with kidney disease, the concerns with respect to side effects and toxicity of opioids are addressed. This is especially relevant with the worldwide increase in the use of opioids for medical and recreational use. MDPI 2017-01-22 /pmc/articles/PMC5297852/ /pubmed/28117754 http://dx.doi.org/10.3390/ijms18010223 Text en © 2017 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mallappallil, Mary
Sabu, Jacob
Friedman, Eli A.
Salifu, Moro
What Do We Know about Opioids and the Kidney?
title What Do We Know about Opioids and the Kidney?
title_full What Do We Know about Opioids and the Kidney?
title_fullStr What Do We Know about Opioids and the Kidney?
title_full_unstemmed What Do We Know about Opioids and the Kidney?
title_short What Do We Know about Opioids and the Kidney?
title_sort what do we know about opioids and the kidney?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297852/
https://www.ncbi.nlm.nih.gov/pubmed/28117754
http://dx.doi.org/10.3390/ijms18010223
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