Selective transition-metal-free vicinal cis-dihydroxylation of saturated hydrocarbons

A transition-metal-free cis-dihydroxylation of saturated hydrocarbons under ambient reaction conditions has been developed. The described approach allows a direct and selective synthesis of vicinal diols. The new reaction thereby proceeds via radical iodination and a sequence of oxidation steps. A b...

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Detalles Bibliográficos
Autores principales: Bering, Luis, Antonchick, Andrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298187/
https://www.ncbi.nlm.nih.gov/pubmed/28451192
http://dx.doi.org/10.1039/c6sc03055f
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author Bering, Luis
Antonchick, Andrey P.
author_facet Bering, Luis
Antonchick, Andrey P.
author_sort Bering, Luis
collection PubMed
description A transition-metal-free cis-dihydroxylation of saturated hydrocarbons under ambient reaction conditions has been developed. The described approach allows a direct and selective synthesis of vicinal diols. The new reaction thereby proceeds via radical iodination and a sequence of oxidation steps. A broad scope of one-pot dual C(sp(3))–H bond functionalization for the selective synthesis of vicinal syn-diols was demonstrated.
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spelling pubmed-52981872017-04-27 Selective transition-metal-free vicinal cis-dihydroxylation of saturated hydrocarbons Bering, Luis Antonchick, Andrey P. Chem Sci Chemistry A transition-metal-free cis-dihydroxylation of saturated hydrocarbons under ambient reaction conditions has been developed. The described approach allows a direct and selective synthesis of vicinal diols. The new reaction thereby proceeds via radical iodination and a sequence of oxidation steps. A broad scope of one-pot dual C(sp(3))–H bond functionalization for the selective synthesis of vicinal syn-diols was demonstrated. Royal Society of Chemistry 2017-01-01 2016-08-22 /pmc/articles/PMC5298187/ /pubmed/28451192 http://dx.doi.org/10.1039/c6sc03055f Text en This journal is © The Royal Society of Chemistry 2016 http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution 3.0 Unported License (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Chemistry
Bering, Luis
Antonchick, Andrey P.
Selective transition-metal-free vicinal cis-dihydroxylation of saturated hydrocarbons
title Selective transition-metal-free vicinal cis-dihydroxylation of saturated hydrocarbons
title_full Selective transition-metal-free vicinal cis-dihydroxylation of saturated hydrocarbons
title_fullStr Selective transition-metal-free vicinal cis-dihydroxylation of saturated hydrocarbons
title_full_unstemmed Selective transition-metal-free vicinal cis-dihydroxylation of saturated hydrocarbons
title_short Selective transition-metal-free vicinal cis-dihydroxylation of saturated hydrocarbons
title_sort selective transition-metal-free vicinal cis-dihydroxylation of saturated hydrocarbons
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298187/
https://www.ncbi.nlm.nih.gov/pubmed/28451192
http://dx.doi.org/10.1039/c6sc03055f
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