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Quantitative liver proteomics identifies FGF19 targets that couple metabolism and proliferation
Fibroblast growth factor 19 (FGF19) is a gut-derived peptide hormone that is produced following activation of Farnesoid X Receptor (FXR). FGF19 is secreted and signals to the liver, where it contributes to the homeostasis of bile acid (BA), lipid and carbohydrate metabolism. FGF19 is a promising the...
Autores principales: | Massafra, Vittoria, Milona, Alexandra, Vos, Harmjan R., Burgering, Boudewijn M. T., van Mil, Saskia W. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298232/ https://www.ncbi.nlm.nih.gov/pubmed/28178326 http://dx.doi.org/10.1371/journal.pone.0171185 |
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