Cargando…

Ligand binding at the A-cluster in full-length or truncated acetyl-CoA synthase studied by X-ray absorption spectroscopy

Bacteria integrate CO(2) reduction and acetyl coenzyme-A (CoA) synthesis in the Wood-Ljungdal pathway. The acetyl-CoA synthase (ACS) active site is a [4Fe4S]-[NiNi] complex (A-cluster). The dinickel site structure (with proximal, p, and distal, d, ions) was studied by X-ray absorption spectroscopy i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schrapers, Peer, Ilina, Julia, Gregg, Christina M., Mebs, Stefan, Jeoung, Jae-Hun, Dau, Holger, Dobbek, Holger, Haumann, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298270/ https://www.ncbi.nlm.nih.gov/pubmed/28178309 http://dx.doi.org/10.1371/journal.pone.0171039

Ejemplares similares

Axial Ligation and Redox Changes at the Cobalt Ion in Cobalamin Bound to Corrinoid Iron-Sulfur Protein (CoFeSP) or in Solution Characterized by XAS and DFT
por: Schrapers, Peer, et al.
Publicado: (2016)

Structural basis for coupled ATP-driven electron transfer in the double-cubane cluster protein
por: Jeoung, Jae-Hun, et al.
Publicado: (2022)

Double‐Cubane [8Fe9S] Clusters: A Novel Nitrogenase‐Related Cofactor in Biology
por: Jeoung, Jae‐Hun, et al.
Publicado: (2020)

X‐ray Crystallography and Vibrational Spectroscopy Reveal the Key Determinants of Biocatalytic Dihydrogen Cycling by [NiFe] Hydrogenases
por: Ilina, Yulia, et al.
Publicado: (2019)

Determining the oxidation state of elements by X-ray crystallography
por: Lennartz, Frank, et al.
Publicado: (2022)

CoA synthase regulates mitotic fidelity via CBP-mediated acetylation
por: Lin, Chao-Chieh, et al.
Publicado: (2018)

Structure, Function, and Mechanism of the Nickel Metalloenzymes, CO Dehydrogenase, and Acetyl-CoA Synthase
por: Can, Mehmet, et al.
Publicado: (2014)

Co-expression of truncated and full-length tau induces severe neurotoxicity
por: Ozcelik, S, et al.
Publicado: (2016)

Crystallographic Characterization of the Carbonylated A-Cluster in Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase
por: Cohen, Steven E., et al.
Publicado: (2020)

Characterization of Methyl- and Acetyl-Ni Intermediates in Acetyl CoA Synthase Formed during Anaerobic CO(2) and CO Fixation
por: Can, Mehmet, et al.
Publicado: (2023)

A Morphing [4Fe‐3S‐nO]‐Cluster within a Carbon Monoxide Dehydrogenase Scaffold
por: Jeoung, Jae‐Hun, et al.
Publicado: (2022)

Characterization of Full-Length and Truncated Recombinant κ-Carrageenase Expressed in Pichia pastoris
por: Yu, Yuan, et al.
Publicado: (2017)

Cloning, characterization, and functional analysis of acetyl-CoA C-acetyltransferase and 3-hydroxy-3-methylglutaryl-CoA synthase genes in Santalum album
por: Niu, Meiyun, et al.
Publicado: (2021)

Operando tracking of oxidation-state changes by coupling electrochemistry with time-resolved X-ray absorption spectroscopy demonstrated for water oxidation by a cobalt-based catalyst film
por: Pasquini, Chiara, et al.
Publicado: (2021)

Acetyl-CoA Carboxylases and Diseases
por: Wang, Yu, et al.
Publicado: (2022)

ACETYL-COA SYNTHETASE REGULATES HISTONE ACETYLATION AND HIPPOCAMPAL MEMORY
por: Mews, Philipp, et al.
Publicado: (2017)

Pleiotrophin Gene Therapy for Peripheral Ischemia: Evaluation of Full-Length and Truncated Gene Variants
por: Fang, Qizhi, et al.
Publicado: (2013)

Decreased expression of acetyl‐CoA synthase 2 promotes metastasis and predicts poor prognosis in hepatocellular carcinoma
por: Sun, Lin, et al.
Publicado: (2017)

A De Novo Designed Trimeric Metalloprotein as a Ni(p) Model of the Acetyl-CoA Synthase
por: Selvan, Dhanashree, et al.
Publicado: (2023)

Acetyl-CoA Metabolism and Histone Acetylation in the Regulation of Aging and Lifespan
por: Bradshaw, Patrick C.
Publicado: (2021)

Chemical Genetics of Acetyl-CoA Carboxylases
por: Zu, Xuyu, et al.
Publicado: (2013)

Acetyl-CoA-mediated autoacetylation of fatty acid synthase as a metabolic switch of de novo lipogenesis in Drosophila
por: Miao, Ting, et al.
Publicado: (2022)

Heterologous Expression of Full-Length and Truncated Human ZIP4 Zinc Transporter in Saccharomyces cerevisiae
por: Liu, Yuting, et al.
Publicado: (2022)

Molecularly Imprinted Electropolymer for a Hexameric Heme Protein with Direct Electron Transfer and Peroxide Electrocatalysis
por: Peng, Lei, et al.
Publicado: (2016)

Structural insights into the light-driven auto-assembly process of the water-oxidizing Mn(4)CaO(5)-cluster in photosystem II
por: Zhang, Miao, et al.
Publicado: (2017)

Acetylation-mediated remodeling of the nucleolus regulates cellular acetyl-CoA responses
por: Houston, Ryan, et al.
Publicado: (2020)

Crystallographic Snapshots of Cyanide- and Water-Bound C-Clusters from Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase(,)
por: Kung, Yan, et al.
Publicado: (2009)

HER2 upregulates fatty acid synthase and acetyl-CoA carboxylase at a translational level in breast cancer cells
por: Yoon, S, et al.
Publicado: (2005)

Increased expression of fatty acid synthase and acetyl-CoA carboxylase in the prefrontal cortex and cerebellum in the valproic acid model of autism
por: Chen, Jianling, et al.
Publicado: (2016)

Discrimination of Curcuma species from Asia using intron length polymorphism markers in genes encoding diketide-CoA synthase and curcumin synthase
por: Liu, Qundong, et al.
Publicado: (2021)

Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta
por: Brown, Jessica A., et al.
Publicado: (2010)

When the inhibitor tells more than the substrate: the cyanide-bound state of a carbon monoxide dehydrogenase
por: Ciaccafava, Alexandre, et al.
Publicado: (2016)

Acetyl-CoA and the Regulation of Metabolism: Mechanisms and Consequences
por: Shi, Lei, et al.
Publicado: (2015)

The dynamic organization of fungal acetyl-CoA carboxylase
por: Hunkeler, Moritz, et al.
Publicado: (2016)

Intracellular Citrate/acetyl-CoA flux and endoplasmic reticulum acetylation: Connectivity is the answer
por: Fernandez-Fuente, Gonzalo, et al.
Publicado: (2022)

The mitochondrion of Plasmodium falciparum is required for cellular acetyl-CoA metabolism and protein acetylation
por: Nair, Sethu C., et al.
Publicado: (2023)

Modulation of plant acetyl-CoA synthetase activity by post-translational lysine acetylation
por: Sofeo, Naazneen, et al.
Publicado: (2023)

Correction to: Discrimination of Curcuma species from Asia using intron length polymorphism markers in genes encoding diketide-CoA synthase and curcumin synthase
por: Liu, Qundong, et al.
Publicado: (2023)

Modeling, molecular docking, probing catalytic binding mode of acetyl-CoA malate synthase G in Brucella melitensis 16M
por: Adi, Pradeepkiran Jangampalli, et al.
Publicado: (2016)

Structural Insights into Microbial One-Carbon Metabolic Enzymes Ni–Fe–S-Dependent Carbon Monoxide Dehydrogenases and Acetyl-CoA Synthases
por: Biester, Alison, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_niuc1j194f6ld2ek73fn2g1kq9