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Cystatin F is a biomarker of prion pathogenesis in mice
Misfolding of the cellular prion protein (PrP(C)) into the scrapie prion protein (PrP(Sc)) results in progressive, fatal, transmissible neurodegenerative conditions termed prion diseases. Experimental and epidemiological evidence point toward a protracted, clinically silent phase in prion diseases,...
Autores principales: | Nuvolone, Mario, Schmid, Nicolas, Miele, Gino, Sorce, Silvia, Moos, Rita, Schori, Christian, Beerli, Roger R., Bauer, Monika, Saudan, Philippe, Dietmeier, Klaus, Lachmann, Ingolf, Linnebank, Michael, Martin, Roland, Kallweit, Ulf, Kana, Veronika, Rushing, Elisabeth J., Budka, Herbert, Aguzzi, Adriano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298286/ https://www.ncbi.nlm.nih.gov/pubmed/28178353 http://dx.doi.org/10.1371/journal.pone.0171923 |
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