Knockdown of HSPA9 induces TP53-dependent apoptosis in human hematopoietic progenitor cells

Myelodysplastic syndromes (MDS) are the most common adult myeloid blood cancers in the US. Patients have increased apoptosis in their bone marrow cells leading to low peripheral blood counts. The full complement of gene mutations that contribute to increased apoptosis in MDS remains unknown. Up to 2...

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Detalles Bibliográficos
Autores principales: Liu, Tuoen, Krysiak, Kilannin, Shirai, Cara Lunn, Kim, Sanghyun, Shao, Jin, Ndonwi, Matthew, Walter, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298293/
https://www.ncbi.nlm.nih.gov/pubmed/28178280
http://dx.doi.org/10.1371/journal.pone.0170470

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