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Large-scale bioactivity analysis of the small-molecule assayed proteome

This study presents an analysis of the small molecule bioactivity profiles across large quantities of diverse protein families represented in PubChem BioAssay. We compared the bioactivity profiles of FDA approved drugs to non-FDA approved compounds, and report several distinct patterns characteristi...

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Detalles Bibliográficos
Autores principales:	Backman, Tyler William H., Evans, Daniel S., Girke, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298297/ https://www.ncbi.nlm.nih.gov/pubmed/28178331 http://dx.doi.org/10.1371/journal.pone.0171413

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