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Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1

HIV-1 particles assemble and bud from the plasma membrane of infected T lymphocytes. Infected macrophages, in contrast, accumulate particles within an apparent intracellular compartment known as the virus-containing compartment or VCC. Many aspects of the formation and function of the VCC remain unc...

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Detalles Bibliográficos
Autores principales:	Hammonds, Jason E., Beeman, Neal, Ding, Lingmei, Takushi, Sarah, Francis, Ashwanth C., Wang, Jaang-Jiun, Melikyan, Gregory B., Spearman, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298340/ https://www.ncbi.nlm.nih.gov/pubmed/28129379 http://dx.doi.org/10.1371/journal.ppat.1006181

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