Resolution of Q Fever–Associated Cryoglobulinemia With Anti-CD20 Monoclonal Antibody Treatment

Immunologic phenomena can complicate chronic infections with Coxiella burnetii (Q fever), including immune complex deposition causing vasculitis, neuropathy, and glomerulonephritis. We describe the case of a man with Q fever endocarditis, mixed cryoglobulinemia, and life-threatening vasculitis drive...

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Detalles Bibliográficos
Autores principales: Hawkins, Kellie L., Janoff, Edward N., Janson, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298489/
https://www.ncbi.nlm.nih.gov/pubmed/28203574
http://dx.doi.org/10.1177/2324709616686612
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author Hawkins, Kellie L.
Janoff, Edward N.
Janson, Robert W.
author_facet Hawkins, Kellie L.
Janoff, Edward N.
Janson, Robert W.
author_sort Hawkins, Kellie L.
collection PubMed
description Immunologic phenomena can complicate chronic infections with Coxiella burnetii (Q fever), including immune complex deposition causing vasculitis, neuropathy, and glomerulonephritis. We describe the case of a man with Q fever endocarditis, mixed cryoglobulinemia, and life-threatening vasculitis driven by immune complex deposition who was successfully treated with B cell depleting therapy (rituximab).
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spelling pubmed-52984892017-02-15 Resolution of Q Fever–Associated Cryoglobulinemia With Anti-CD20 Monoclonal Antibody Treatment Hawkins, Kellie L. Janoff, Edward N. Janson, Robert W. J Investig Med High Impact Case Rep Case Report Immunologic phenomena can complicate chronic infections with Coxiella burnetii (Q fever), including immune complex deposition causing vasculitis, neuropathy, and glomerulonephritis. We describe the case of a man with Q fever endocarditis, mixed cryoglobulinemia, and life-threatening vasculitis driven by immune complex deposition who was successfully treated with B cell depleting therapy (rituximab). SAGE Publications 2017-01-01 /pmc/articles/PMC5298489/ /pubmed/28203574 http://dx.doi.org/10.1177/2324709616686612 Text en © 2017 American Federation for Medical Research http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution 3.0 License (http://www.creativecommons.org/licenses/by/3.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Hawkins, Kellie L.
Janoff, Edward N.
Janson, Robert W.
Resolution of Q Fever–Associated Cryoglobulinemia With Anti-CD20 Monoclonal Antibody Treatment
title Resolution of Q Fever–Associated Cryoglobulinemia With Anti-CD20 Monoclonal Antibody Treatment
title_full Resolution of Q Fever–Associated Cryoglobulinemia With Anti-CD20 Monoclonal Antibody Treatment
title_fullStr Resolution of Q Fever–Associated Cryoglobulinemia With Anti-CD20 Monoclonal Antibody Treatment
title_full_unstemmed Resolution of Q Fever–Associated Cryoglobulinemia With Anti-CD20 Monoclonal Antibody Treatment
title_short Resolution of Q Fever–Associated Cryoglobulinemia With Anti-CD20 Monoclonal Antibody Treatment
title_sort resolution of q fever–associated cryoglobulinemia with anti-cd20 monoclonal antibody treatment
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298489/
https://www.ncbi.nlm.nih.gov/pubmed/28203574
http://dx.doi.org/10.1177/2324709616686612
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