When Nothing Else Works: Fresh Frozen Plasma in the Treatment of Progressive, Refractory Angiotensin-Converting Enzyme Inhibitor–Induced Angioedema

Angioedema is a severe form of an allergic reaction characterized by the localized edematous swelling of the dermis and subcutaneous tissues. Angiotensin-converting enzyme inhibitor-induced angioedema (ACEI-IA) is an allergic reaction that can be severe in some cases requiring advanced management me...

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Autores principales: Chaaya, Gerard, Afridi, Faraz, Faiz, Arfa, Ashraf, Ali, Ali, Mahrukh, Castiglioni, Analia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2017
Materias:
Pulmonology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298931/
https://www.ncbi.nlm.nih.gov/pubmed/28191376
http://dx.doi.org/10.7759/cureus.972
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author Chaaya, Gerard
Afridi, Faraz
Faiz, Arfa
Ashraf, Ali
Ali, Mahrukh
Castiglioni, Analia
author_facet Chaaya, Gerard
Afridi, Faraz
Faiz, Arfa
Ashraf, Ali
Ali, Mahrukh
Castiglioni, Analia
author_sort Chaaya, Gerard
collection PubMed
description Angioedema is a severe form of an allergic reaction characterized by the localized edematous swelling of the dermis and subcutaneous tissues. Angiotensin-converting enzyme inhibitor-induced angioedema (ACEI-IA) is an allergic reaction that can be severe in some cases requiring advanced management measures. Fresh frozen plasma has been used off-labeled in some case reports to improve and to prevent worsening of the angioedema in a few cases of ACEI-IA. We are reporting this case to increase the awareness of physicians and to widen their therapeutic options when encountering this clinically significant condition. 
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spelling pubmed-52989312017-02-10 When Nothing Else Works: Fresh Frozen Plasma in the Treatment of Progressive, Refractory Angiotensin-Converting Enzyme Inhibitor–Induced Angioedema Chaaya, Gerard Afridi, Faraz Faiz, Arfa Ashraf, Ali Ali, Mahrukh Castiglioni, Analia Cureus Pulmonology Angioedema is a severe form of an allergic reaction characterized by the localized edematous swelling of the dermis and subcutaneous tissues. Angiotensin-converting enzyme inhibitor-induced angioedema (ACEI-IA) is an allergic reaction that can be severe in some cases requiring advanced management measures. Fresh frozen plasma has been used off-labeled in some case reports to improve and to prevent worsening of the angioedema in a few cases of ACEI-IA. We are reporting this case to increase the awareness of physicians and to widen their therapeutic options when encountering this clinically significant condition.  Cureus 2017-01-11 /pmc/articles/PMC5298931/ /pubmed/28191376 http://dx.doi.org/10.7759/cureus.972 Text en Copyright © 2017, Chaaya et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pulmonology
Chaaya, Gerard
Afridi, Faraz
Faiz, Arfa
Ashraf, Ali
Ali, Mahrukh
Castiglioni, Analia
When Nothing Else Works: Fresh Frozen Plasma in the Treatment of Progressive, Refractory Angiotensin-Converting Enzyme Inhibitor–Induced Angioedema
title When Nothing Else Works: Fresh Frozen Plasma in the Treatment of Progressive, Refractory Angiotensin-Converting Enzyme Inhibitor–Induced Angioedema
title_full When Nothing Else Works: Fresh Frozen Plasma in the Treatment of Progressive, Refractory Angiotensin-Converting Enzyme Inhibitor–Induced Angioedema
title_fullStr When Nothing Else Works: Fresh Frozen Plasma in the Treatment of Progressive, Refractory Angiotensin-Converting Enzyme Inhibitor–Induced Angioedema
title_full_unstemmed When Nothing Else Works: Fresh Frozen Plasma in the Treatment of Progressive, Refractory Angiotensin-Converting Enzyme Inhibitor–Induced Angioedema
title_short When Nothing Else Works: Fresh Frozen Plasma in the Treatment of Progressive, Refractory Angiotensin-Converting Enzyme Inhibitor–Induced Angioedema
title_sort when nothing else works: fresh frozen plasma in the treatment of progressive, refractory angiotensin-converting enzyme inhibitor–induced angioedema
topic Pulmonology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298931/
https://www.ncbi.nlm.nih.gov/pubmed/28191376
http://dx.doi.org/10.7759/cureus.972
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