Cargando…

Nicotine Elicits Convulsive Seizures by Activating Amygdalar Neurons

Nicotinic acetylcholine (nACh) receptors are implicated in the pathogenesis of epileptic disorders; however, the mechanisms of nACh receptors in seizure generation remain unknown. Here, we performed behavioral and immunohistochemical studies in mice and rats to clarify the mechanisms underlying nico...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iha, Higor A., Kunisawa, Naofumi, Shimizu, Saki, Tokudome, Kentaro, Mukai, Takahiro, Kinboshi, Masato, Ikeda, Akio, Ito, Hidefumi, Serikawa, Tadao, Ohno, Yukihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298991/ https://www.ncbi.nlm.nih.gov/pubmed/28232801 http://dx.doi.org/10.3389/fphar.2017.00057

Ejemplares similares

PT667. Nicotine evokes convulsive seizures by activating amygdala neurons partly through α7nACh receptors
por: Iha, Higor A., et al.
Publicado: (2016)

A Missense Mutation of the Gene Encoding Synaptic Vesicle Glycoprotein 2A (SV2A) Confers Seizure Susceptibility by Disrupting Amygdalar Synaptic GABA Release
por: Tokudome, Kentaro, et al.
Publicado: (2016)

Imbalance of glutamatergic and GABAergic neurotransmission in audiogenic seizure-susceptible Leucine-rich glioma-inactivated 1 (Lgi1)-mutant rats
por: Kinboshi, Masato, et al.
Publicado: (2023)

PT673. Pharmacological analysis of nicotine-induced tremor
por: Kunisawa, Naofumi, et al.
Publicado: (2016)

Mechanisms Underlying Dopaminergic Regulation of Nicotine-Induced Kinetic Tremor
por: Kato, Masaki, et al.
Publicado: (2022)

Down-Regulation of Astrocytic Kir4.1 Channels during the Audiogenic Epileptogenesis in Leucine-Rich Glioma-Inactivated 1 (Lgi1) Mutant Rats
por: Kinboshi, Masato, et al.
Publicado: (2019)

PT678. Enhancement of the accumbal dopamine release by the gene mutation of synaptic vesicle protein 2A (Sv2a(L174Q))
por: Tokudome, Kentaro, et al.
Publicado: (2016)

Synaptic vesicle glycoprotein 2A (SV2A) regulates kindling epileptogenesis via GABAergic neurotransmission
por: Tokudome, Kentaro, et al.
Publicado: (2016)

Inhibition of Inwardly Rectifying Potassium (Kir) 4.1 Channels Facilitates Brain-Derived Neurotrophic Factor (BDNF) Expression in Astrocytes
por: Kinboshi, Masato, et al.
Publicado: (2017)

Antiepileptic Drugs Elevate Astrocytic Kir4.1 Expression in the Rat Limbic Region
por: Mukai, Takahiro, et al.
Publicado: (2018)

Role of Astrocytic Inwardly Rectifying Potassium (Kir) 4.1 Channels in Epileptogenesis
por: Kinboshi, Masato, et al.
Publicado: (2020)

Antipsychotic Treatment of Behavioral and Psychological Symptoms of Dementia (BPSD): Management of Extrapyramidal Side Effects
por: Ohno, Yukihiro, et al.
Publicado: (2019)

Emerging Roles of Astrocyte Kir4.1 Channels in the Pathogenesis and Treatment of Brain Diseases
por: Ohno, Yukihiro, et al.
Publicado: (2021)

Inwardly Rectifying Potassium Channel Kir4.1 as a Novel Modulator of BDNF Expression in Astrocytes
por: Ohno, Yukihiro, et al.
Publicado: (2018)

Glycine-Binding Site Stimulants of NMDA Receptors Alleviate Extrapyramidal Motor Disorders by Activating the Nigrostriatal Dopaminergic Pathway
por: Shimizu, Saki, et al.
Publicado: (2017)

Convulsive Seizures
por: Kahn, Eugen
Publicado: (1943)

Hcn1 Is a Tremorgenic Genetic Component in a Rat Model of Essential Tremor
por: Ohno, Yukihiro, et al.
Publicado: (2015)

Prevalence and mortality of epilepsies with convulsive and non-convulsive seizures in Kilifi, Kenya
por: Kariuki, Symon M, et al.
Publicado: (2021)

The Prehospital Predictors of Tracheal Intubation for in Patients who Experience Convulsive Seizures in the Emergency Department
por: Sato, Kenichiro, et al.
Publicado: (2017)

Advances on genetic rat models of epilepsy
por: Serikawa, Tadao, et al.
Publicado: (2014)

Late Seizures after Stroke in Clinical Practice: The Prevalence of Non-convulsive Seizures
por: Miyaji, Yosuke, et al.
Publicado: (2017)

Febrile seizures and convulsions with mild gastroenteritis: age-dependent acute symptomatic seizures
por: Cappellari, Alberto M., et al.
Publicado: (2023)

Non-convulsive seizure clustering misdiagnosed as vertebrobasilar insufficiency
por: Chen, Yu-Shiue, et al.
Publicado: (2020)

Dementia with non-convulsive seizures: a case report
por: Chen, Yu-Shiue, et al.
Publicado: (2021)

An amygdalar neural ensemble that encodes the unpleasantness of pain
por: Corder, Gregory, et al.
Publicado: (2018)

Organization of primate amygdalar–thalamic pathways for emotions
por: Timbie, Clare, et al.
Publicado: (2020)

Connectivity characterization of the mouse basolateral amygdalar complex
por: Hintiryan, Houri, et al.
Publicado: (2021)

Risk of convulsive epilepsy following acute seizures in Kenyan children
por: Bistervels, Ingrid M., et al.
Publicado: (2016)

Risk Factors Associated With Hyperammonemia Following Unprovoked Convulsive Seizures
por: Karim, Nurose, et al.
Publicado: (2020)

Heartbreakers—Cardiac Stress After Uncomplicated Generalized Convulsive Seizures
por: Gaspard, Nicolas
Publicado: (2019)

Effect of fenfluramine on convulsive seizures in CDKL5 deficiency disorder
por: Devinsky, Orrin, et al.
Publicado: (2021)

Ketamine-induced generalized convulsive seizure during procedural sedation
por: Kim, Ji Hoon, et al.
Publicado: (2021)

Non-convulsive epiletic seizure after electroconvulsive therapy session
por: Llovera García, L., et al.
Publicado: (2023)

Amygdalar and hippocampal substrates of anxious temperament differ in their heritability
por: Oler, Jonathan A., et al.
Publicado: (2010)

Organizational principles of amygdalar input-output neuronal circuits
por: Huang, Limeng, et al.
Publicado: (2021)

Prefrontal-amygdalar oscillations related to social behavior in mice
por: Kuga, Nahoko, et al.
Publicado: (2022)

IS A GRANDMAL SEIZURE NECESSARY AND SUFFICIENT FOR THE EFFICACY OF ELECTRO CONVULSIVE THERAPY?
por: Verghese, Abraham
Publicado: (2000)

Clavulanic acid does not affect convulsions in acute seizure tests in mice
por: Gasior, Maciej, et al.
Publicado: (2011)

Buccal midazolam for pediatric convulsive seizures: efficacy, safety, and patient acceptability
por: Anderson, Mark
Publicado: (2013)

Bilateral Paramedian Thalamic Infarction Initially Presenting as a Convulsive Seizure
por: Wang, Jianping, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_7s6d583stke93tmg4hhlohsl39