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Novel Structural Parameters of Ig–Ag Complexes Yield a Quantitative Description of Interaction Specificity and Binding Affinity

Antibody–antigen complexes challenge our understanding, as analyses to date failed to unveil the key determinants of binding affinity and interaction specificity. We partially fill this gap based on novel quantitative analyses using two standardized databases, the IMGT/3Dstructure-DB and the structu...

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Detalles Bibliográficos
Autores principales:	Marillet, Simon, Lefranc, Marie-Paule, Boudinot, Pierre, Cazals, Frédéric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298999/ https://www.ncbi.nlm.nih.gov/pubmed/28232828 http://dx.doi.org/10.3389/fimmu.2017.00034

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