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Fibronectin and androgen receptor expression data in prostate cancer obtained from a RNA-sequencing bioinformatics analysis
Prostate cancer is the second most commonly diagnosed male cancer in the world. The molecular mechanisms underlying its development and progression are still unclear. Here we show analysis of a prostate cancer RNA-sequencing dataset that was originally generated by Ren et al. [3] from the prostate t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299139/ https://www.ncbi.nlm.nih.gov/pubmed/28210664 http://dx.doi.org/10.1016/j.dib.2017.01.016 |
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author | Das, Dibash K. Ali, Thahmina Krampis, Konstantinos Ogunwobi, Olorunseun O. |
author_facet | Das, Dibash K. Ali, Thahmina Krampis, Konstantinos Ogunwobi, Olorunseun O. |
author_sort | Das, Dibash K. |
collection | PubMed |
description | Prostate cancer is the second most commonly diagnosed male cancer in the world. The molecular mechanisms underlying its development and progression are still unclear. Here we show analysis of a prostate cancer RNA-sequencing dataset that was originally generated by Ren et al. [3] from the prostate tumor and adjacent normal tissues of 14 patients. The data presented here was analyzed using our RNA-sequencing bioinformatics analysis pipeline implemented on the bioinformatics web platform, Galaxy. The relative expression of fibronectin (FN1) and the androgen receptor (AR) were calculated in fragments per kilobase of transcript per million mapped reads, and represented in FPKM unit. A subanalysis is also shown for data from three patients, that includes the relative expression of FN1 and AR and their fold change. For interpretation and discussion, please refer to the article, “miR-1207-3p regulates the androgen receptor in prostate cancer via FNDC1/fibronectin” [1] by Das et al. |
format | Online Article Text |
id | pubmed-5299139 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-52991392017-02-16 Fibronectin and androgen receptor expression data in prostate cancer obtained from a RNA-sequencing bioinformatics analysis Das, Dibash K. Ali, Thahmina Krampis, Konstantinos Ogunwobi, Olorunseun O. Data Brief Data Article Prostate cancer is the second most commonly diagnosed male cancer in the world. The molecular mechanisms underlying its development and progression are still unclear. Here we show analysis of a prostate cancer RNA-sequencing dataset that was originally generated by Ren et al. [3] from the prostate tumor and adjacent normal tissues of 14 patients. The data presented here was analyzed using our RNA-sequencing bioinformatics analysis pipeline implemented on the bioinformatics web platform, Galaxy. The relative expression of fibronectin (FN1) and the androgen receptor (AR) were calculated in fragments per kilobase of transcript per million mapped reads, and represented in FPKM unit. A subanalysis is also shown for data from three patients, that includes the relative expression of FN1 and AR and their fold change. For interpretation and discussion, please refer to the article, “miR-1207-3p regulates the androgen receptor in prostate cancer via FNDC1/fibronectin” [1] by Das et al. Elsevier 2017-02-03 /pmc/articles/PMC5299139/ /pubmed/28210664 http://dx.doi.org/10.1016/j.dib.2017.01.016 Text en © 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Data Article Das, Dibash K. Ali, Thahmina Krampis, Konstantinos Ogunwobi, Olorunseun O. Fibronectin and androgen receptor expression data in prostate cancer obtained from a RNA-sequencing bioinformatics analysis |
title | Fibronectin and androgen receptor expression data in prostate cancer obtained from a RNA-sequencing bioinformatics analysis |
title_full | Fibronectin and androgen receptor expression data in prostate cancer obtained from a RNA-sequencing bioinformatics analysis |
title_fullStr | Fibronectin and androgen receptor expression data in prostate cancer obtained from a RNA-sequencing bioinformatics analysis |
title_full_unstemmed | Fibronectin and androgen receptor expression data in prostate cancer obtained from a RNA-sequencing bioinformatics analysis |
title_short | Fibronectin and androgen receptor expression data in prostate cancer obtained from a RNA-sequencing bioinformatics analysis |
title_sort | fibronectin and androgen receptor expression data in prostate cancer obtained from a rna-sequencing bioinformatics analysis |
topic | Data Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299139/ https://www.ncbi.nlm.nih.gov/pubmed/28210664 http://dx.doi.org/10.1016/j.dib.2017.01.016 |
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