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NOTCH1 Mutations in Aortic Stenosis: Association with Osteoprotegerin/RANK/RANKL
Background. The NOTCH pathway is known to be important in the pathogenesis of calcific aortic valve disease, possibly through regulators of osteoprotegerin (OPG), receptor activator of nuclear factor κB (RANK), and its ligand (RANKL) system. The purpose of the present study was to search for possibl...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299165/ https://www.ncbi.nlm.nih.gov/pubmed/28246602 http://dx.doi.org/10.1155/2017/6917907 |