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NOTCH1 Mutations in Aortic Stenosis: Association with Osteoprotegerin/RANK/RANKL

Background. The NOTCH pathway is known to be important in the pathogenesis of calcific aortic valve disease, possibly through regulators of osteoprotegerin (OPG), receptor activator of nuclear factor κB (RANK), and its ligand (RANKL) system. The purpose of the present study was to search for possibl...

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Detalles Bibliográficos
Autores principales: Irtyuga, Olga, Malashicheva, Anna, Zhiduleva, Ekaterina, Freylikhman, Olga, Rotar, Oxana, Bäck, Magnus, Tarnovskaya, Svetlana, Kostareva, Anna, Moiseeva, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299165/
https://www.ncbi.nlm.nih.gov/pubmed/28246602
http://dx.doi.org/10.1155/2017/6917907