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Decreased Tissue COX5B Expression and Mitochondrial Dysfunction during Sepsis-Induced Kidney Injury in Rats

Background. Sepsis is defined as a life-threatening organ dysfunction due to a dysregulated host response to infection. Sepsis is the dominant cause of acute kidney injury (AKI), accounting for nearly 50% of episodes of acute renal failure. Signaling cascades and pathways within the kidney are large...

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Detalles Bibliográficos
Autores principales: Hinkelbein, Jochen, Böhm, Lennert, Braunecker, Stefan, Adler, Christoph, De Robertis, Edoardo, Cirillo, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299166/
https://www.ncbi.nlm.nih.gov/pubmed/28246552
http://dx.doi.org/10.1155/2017/8498510