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Redox and pH Responsive Poly (Amidoamine) Dendrimer-Heparin Conjugates via Disulfide Linkages for Letrozole Delivery

Heparin (Hep) conjugated to poly (amidoamine) dendrimer G3.5 (P) via redox-sensitive disulfide bond (P-SS-Hep) was studied. The redox and pH dual-responsive nanocarriers were prepared by a simple method that minimized many complex steps as previous studies. The functional characterization of G3.5 co...

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Detalles Bibliográficos
Autores principales: Nguyen, Thanh Luan, Nguyen, Thi Hiep, Nguyen, Cuu Khoa, Nguyen, Dai Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299214/
https://www.ncbi.nlm.nih.gov/pubmed/28246606
http://dx.doi.org/10.1155/2017/8589212