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Improving Theory of Mind in Schizophrenia by Targeting Cognition and Metacognition with Computerized Cognitive Remediation: A Multiple Case Study

Schizophrenia is associated with deficits in theory of mind (ToM) (i.e., the ability to infer the mental states of others) and cognition. Associations have often been reported between cognition and ToM, and ToM mediates the relationship between impaired cognition and impaired functioning in schizoph...

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Autores principales: Thibaudeau, Élisabeth, Cellard, Caroline, Reeder, Clare, Wykes, Til, Ivers, Hans, Maziade, Michel, Lavoie, Marie-Audrey, Pothier, William, Achim, Amélie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299218/
https://www.ncbi.nlm.nih.gov/pubmed/28246557
http://dx.doi.org/10.1155/2017/7203871
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author Thibaudeau, Élisabeth
Cellard, Caroline
Reeder, Clare
Wykes, Til
Ivers, Hans
Maziade, Michel
Lavoie, Marie-Audrey
Pothier, William
Achim, Amélie M.
author_facet Thibaudeau, Élisabeth
Cellard, Caroline
Reeder, Clare
Wykes, Til
Ivers, Hans
Maziade, Michel
Lavoie, Marie-Audrey
Pothier, William
Achim, Amélie M.
author_sort Thibaudeau, Élisabeth
collection PubMed
description Schizophrenia is associated with deficits in theory of mind (ToM) (i.e., the ability to infer the mental states of others) and cognition. Associations have often been reported between cognition and ToM, and ToM mediates the relationship between impaired cognition and impaired functioning in schizophrenia. Given that cognitive deficits could act as a limiting factor for ToM, this study investigated whether a cognitive remediation therapy (CRT) that targets nonsocial cognition and metacognition could improve ToM in schizophrenia. Four men with schizophrenia received CRT. Assessments of ToM, cognition, and metacognition were conducted at baseline and posttreatment as well as three months and 1 year later. Two patients reached a significant improvement in ToM immediately after treatment whereas at three months after treatment all four cases reached a significant improvement, which was maintained through 1 year after treatment for all three cases that remained in the study. Improvements in ToM were accompanied by significant improvements in the most severely impaired cognitive functions at baseline or by improvements in metacognition. This study establishes that a CRT program that does not explicitly target social abilities can improve ToM.
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spelling pubmed-52992182017-02-28 Improving Theory of Mind in Schizophrenia by Targeting Cognition and Metacognition with Computerized Cognitive Remediation: A Multiple Case Study Thibaudeau, Élisabeth Cellard, Caroline Reeder, Clare Wykes, Til Ivers, Hans Maziade, Michel Lavoie, Marie-Audrey Pothier, William Achim, Amélie M. Schizophr Res Treatment Research Article Schizophrenia is associated with deficits in theory of mind (ToM) (i.e., the ability to infer the mental states of others) and cognition. Associations have often been reported between cognition and ToM, and ToM mediates the relationship between impaired cognition and impaired functioning in schizophrenia. Given that cognitive deficits could act as a limiting factor for ToM, this study investigated whether a cognitive remediation therapy (CRT) that targets nonsocial cognition and metacognition could improve ToM in schizophrenia. Four men with schizophrenia received CRT. Assessments of ToM, cognition, and metacognition were conducted at baseline and posttreatment as well as three months and 1 year later. Two patients reached a significant improvement in ToM immediately after treatment whereas at three months after treatment all four cases reached a significant improvement, which was maintained through 1 year after treatment for all three cases that remained in the study. Improvements in ToM were accompanied by significant improvements in the most severely impaired cognitive functions at baseline or by improvements in metacognition. This study establishes that a CRT program that does not explicitly target social abilities can improve ToM. Hindawi Publishing Corporation 2017 2017-01-26 /pmc/articles/PMC5299218/ /pubmed/28246557 http://dx.doi.org/10.1155/2017/7203871 Text en Copyright © 2017 Élisabeth Thibaudeau et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Thibaudeau, Élisabeth
Cellard, Caroline
Reeder, Clare
Wykes, Til
Ivers, Hans
Maziade, Michel
Lavoie, Marie-Audrey
Pothier, William
Achim, Amélie M.
Improving Theory of Mind in Schizophrenia by Targeting Cognition and Metacognition with Computerized Cognitive Remediation: A Multiple Case Study
title Improving Theory of Mind in Schizophrenia by Targeting Cognition and Metacognition with Computerized Cognitive Remediation: A Multiple Case Study
title_full Improving Theory of Mind in Schizophrenia by Targeting Cognition and Metacognition with Computerized Cognitive Remediation: A Multiple Case Study
title_fullStr Improving Theory of Mind in Schizophrenia by Targeting Cognition and Metacognition with Computerized Cognitive Remediation: A Multiple Case Study
title_full_unstemmed Improving Theory of Mind in Schizophrenia by Targeting Cognition and Metacognition with Computerized Cognitive Remediation: A Multiple Case Study
title_short Improving Theory of Mind in Schizophrenia by Targeting Cognition and Metacognition with Computerized Cognitive Remediation: A Multiple Case Study
title_sort improving theory of mind in schizophrenia by targeting cognition and metacognition with computerized cognitive remediation: a multiple case study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299218/
https://www.ncbi.nlm.nih.gov/pubmed/28246557
http://dx.doi.org/10.1155/2017/7203871
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