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Glucose deficit triggers tau pathology and synaptic dysfunction in a tauopathy mouse model

Clinical investigations have highlighted a biological link between reduced brain glucose metabolism and Alzheimer's disease (AD). Previous studies showed that glucose deprivation may influence amyloid beta formation in vivo but no data are available on the effect that this condition might have...

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Detalles Bibliográficos
Autores principales: Lauretti, E, Li, J-G, Di Meco, A, Praticò, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299397/
https://www.ncbi.nlm.nih.gov/pubmed/28140402
http://dx.doi.org/10.1038/tp.2016.296