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Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues

We investigated whether the developmental stage of mouse cardiac fibroblasts (CFs) influences the formation and function of engineered cardiac tissues made of mouse embryonic stem cell-derived cardiomyocytes (mESC-CMs). Engineered cardiac tissue patches were fabricated by encapsulating pure mESC-CMs...

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Detalles Bibliográficos
Autores principales: Liau, Brian, Jackman, Christopher P., Li, Yanzhen, Bursac, Nenad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299411/
https://www.ncbi.nlm.nih.gov/pubmed/28181589
http://dx.doi.org/10.1038/srep42290