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Sirtuin1 protects endothelial Caveolin-1 expression and preserves endothelial function via suppressing miR-204 and endoplasmic reticulum stress
Sirtuin1 (Sirt1) is a class III histone deacetylase that regulates a variety of physiological processes, including endothelial function. Caveolin1 (Cav1) is also an important determinant of endothelial function. We asked if Sirt1 governs endothelial Cav1 and endothelial function by regulating miR-20...
Autores principales: | Kassan, M., Vikram, A., Kim, Y. R., Li, Q., Kassan, A., Patel, H. H., Kumar, S., Gabani, M., Liu, J., Jacobs, J. S., Irani, K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299412/ https://www.ncbi.nlm.nih.gov/pubmed/28181559 http://dx.doi.org/10.1038/srep42265 |
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