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Lumican Peptides: Rational Design Targeting ALK5/TGFBRI
Lumican, a small leucine rich proteoglycan (SLRP), is a component of extracellular matrix which also functions as a matrikine regulating multiple cell activities. In the cornea, lumican maintains corneal transparency by regulating collagen fibrillogenesis, promoting corneal epithelial wound healing,...
Autores principales: | Gesteira, Tarsis Ferreira, Coulson-Thomas, Vivien J., Yuan, Yong, Zhang, Jianhua, Nader, Helena B., Kao, Winston W.-Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299588/ https://www.ncbi.nlm.nih.gov/pubmed/28181591 http://dx.doi.org/10.1038/srep42057 |
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