Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy

Dystrophin deficiency is the genetic basis for Duchenne muscular dystrophy (DMD), but the cellular basis of progressive myofiber death in DMD is not fully understood. Using two dystrophin-deficient mdx mouse models, we find that the mitochondrial dysfunction is among the earliest cellular deficits o...

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Detalles Bibliográficos
Autores principales: Vila, Maria C, Rayavarapu, Sree, Hogarth, Marshall W, Van der Meulen, Jack H, Horn, Adam, Defour, Aurelia, Takeda, Shin'ichi, Brown, Kristy J, Hathout, Yetrib, Nagaraju, Kanneboyina, Jaiswal, Jyoti K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299714/
https://www.ncbi.nlm.nih.gov/pubmed/27834955
http://dx.doi.org/10.1038/cdd.2016.127

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