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Determination of biological activity of gonadotropins hCG and FSH by Förster resonance energy transfer based biosensors

Determination of biological activity of gonadotropin hormones is essential in reproductive medicine and pharmaceutical manufacturing of the hormonal preparations. The aim of the study was to adopt a G-protein coupled receptor (GPCR)-mediated signal transduction pathway based assay for quantification...

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Detalles Bibliográficos
Autores principales: Mazina, Olga, Allikalt, Anni, Tapanainen, Juha S., Salumets, Andres, Rinken, Ago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299843/
https://www.ncbi.nlm.nih.gov/pubmed/28181555
http://dx.doi.org/10.1038/srep42219